Technology for the future is a daily objective at Dermazone.
“Our patent portfolio and on-going discovery is at the heart of our vision: to enhance the health and wellness of lives everywhere, in all ways, through every stage of life. Our second-generation technology, NLP, has led us to applications far beyond skin science such as food and beverage, oral supplements and animal health.”
Deborah Duffey, President
When an all-natural GRAS composition is coupled with custom engineering, ordinary products become extraordinary.
Enyzymatic Degradation
Content dumping
Lipase
Esterase
Phospholipidase
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Making NLP Nanotechnology® liposomes: a simple process
Illustration of the NLP liposome
- Phospholipid chain creates the nanosphere's structure: two separate layers
- Hydrophilic (water soluble) active ingredients
- Lipophilic (oil soluble) active ingredients
- Passenger Molecule Loading
- Solubility
- Load Enhancement
Delivery of AI with NLP
Enyzymatic Degradation
Content dumping
Lipase
Esterase
Phospholipidase
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Mode of Activation
![technology_skin_ani technology_skin_ani](https://1pz93a.p3cdn1.secureserver.net/wp-content/uploads/2020/05/technology_skin_ani.gif)
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Cross-section of skin showing Lyphazome® penetration
Migration of microspheres to stratum corneum and granulosum
Time release of cargo
Improved epidermal penetration
Depot Effect
- Lipid Similarity
- Biocompatible
![rhodamine skin compressed rhodamine skin compressed](https://1pz93a.p3cdn1.secureserver.net/wp-content/uploads/2020/05/rhodamine-skin-compressed.jpg)
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Lyphazome® penetrating upper layers of skin
Rhodamine loaded Lyphazome® in skin
UV Spectroscopy
NLP has 4 important characteristcs
Patent-protected encapsulation for nano-enabled consumer products
![Natural, Biodegradable, GRAS Natural, Biodegradable, GRAS](https://1pz93a.p3cdn1.secureserver.net/wp-content/uploads/2020/03/important-characteristics-1.jpg)
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![Simple, Inexpensive, Manufacturing Simple, Inexpensive, Manufacturing](https://1pz93a.p3cdn1.secureserver.net/wp-content/uploads/2020/03/important-characteristics-2.jpg)
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![Patent Protected Patent Protected](https://1pz93a.p3cdn1.secureserver.net/wp-content/uploads/2020/03/important-characteristics-3.jpg)
![Patent Protected Patent Protected](https://1pz93a.p3cdn1.secureserver.net/wp-content/uploads/2020/03/important-characteristics-3.jpg)
![Makes Active Ingredients Work Better Makes Active Ingredients Work Better](https://1pz93a.p3cdn1.secureserver.net/wp-content/uploads/2020/03/important-characteristics-4.jpg)
![Makes Active Ingredients Work Better Makes Active Ingredients Work Better](https://1pz93a.p3cdn1.secureserver.net/wp-content/uploads/2020/03/important-characteristics-4.jpg)
![nlp-nanotechnology-capabilities NLP Nanotechnology Capabilities](https://1pz93a.p3cdn1.secureserver.net/wp-content/uploads/2020/03/nlp-nanotechnology-capabilities.jpg)
![nlp-nanotechnology-capabilities NLP Nanotechnology Capabilities](https://1pz93a.p3cdn1.secureserver.net/wp-content/uploads/2020/03/nlp-nanotechnology-capabilities.jpg)
NLP benefits:
- Low cost to manufacture
- Incorporates into existing manufacturing processes
- All-natural ingredients
"NLP" = nano-lipidic particle (NuVessl's patented technology)
"AI" = Active Ingredient
White pH Range of AI
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Avoids NLP breakdown by saliva or stomack acids
Dial-a-size Capability
Custom AI Release
Greater AI Bio-availability & Uptake
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Faster & longer-lasting effects
Increased AI Stability
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Greater shelf life
Mask or Enhance Taste/Smell
Optical Clarity
Multiple AI Together
Hydro & Lipophilic
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Water- & oil- soluble molecules can be combined in 1 NLP
Incompatible AI
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